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Red Light Therapy for Angiogenesis (promotion of)

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PBM with red and near-infrared light has been reported to stimulate angiogenesis in numerous cell culture studies (Zhang et al. 2022, Stepanov et al. 2022, Winter et al. 2018, Lim et al. 2011) and rodents with hindlimb ischemia (Huang et al. 2021, Lohr et al. 2013), ischemic flap (Dungel et al. 2014) and cutaneous wounds (de Sousa et al. 2013). Blue light showed angiogenic effects in one rat study (Dungel et al. 2014), but not in another (de Sousa et al. 2013). Green light showed angiogenic effects in one rat study (de Sousa et al. 2013).

Evidence Summary

๐Ÿ 9 animal studies (mouse, rat, rabbit) ๐Ÿงช 7 cell culture studies

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Research Basis

This content is informed by 47+ published peer-reviewed studies on photobiomodulation.