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neurologicalemerging evidence

Traumatic Brain Injury / Concussion

Published: Last updated:

Source: Clinical Research (Emerging)

Transcranial PBM protocol for post-concussion syndrome and chronic TBI symptoms. NIR light at 810nm has the best penetration through the skull to reach cortical brain tissue. This is an emerging application with promising but limited clinical evidence.

Protocol Parameters

ConditionTraumatic Brain Injury
Wavelengths810nm, 830nm, 850nm
Dosage10-30 J/cm² transcranially
Irradiance50-100 mW/cm² at scalp
Duration10-20 minutes
Frequency3x per week for 6+ weeks
Body Zonehead
Evidence LevelEmerging

Mechanism of Action

Transcranial NIR light penetrates the skull (approximately 2-3% transmission) and is absorbed by cytochrome c oxidase in cortical neurons. This improves neuronal mitochondrial function, reduces neuroinflammation, promotes neuroplasticity, and enhances cerebral blood flow. The net effect is improved cognitive function and reduced post-concussion symptoms.

Key Studies

  • Naeser et al. (2014) - Transcranial LED for chronic TBI
  • Hamblin (2016) - Shining light on the head: PBM for brain disorders
  • Salehpour et al. (2018) - Transcranial PBM for brain injury review

Treatment Tips

  • *810nm has best skull penetration among common wavelengths
  • *Apply to forehead, temporal regions, and posterior skull
  • *This is experimental - coordinate with neurological care team
  • *Track cognitive symptoms with standardized assessments

Contraindications

  • !Active intracranial hemorrhage
  • !History of seizures (use caution)
  • !Cranial defects or shunts

Research Basis

This content is informed by 47+ published peer-reviewed studies on photobiomodulation.