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woundemerging evidence

Bone Fracture Healing

Published: Last updated:

Source: Preclinical + Clinical Research

Protocol for supporting bone fracture healing using NIR wavelengths to penetrate to the fracture site. PBM may accelerate callus formation and bone remodeling when used as an adjunct to standard orthopedic treatment.

Protocol Parameters

ConditionBone Fracture
Wavelengths810nm, 830nm, 850nm
Dosage4-8 J/cm²
Irradiance50-100 mW/cm²
Duration5-10 minutes over fracture site
FrequencyDaily for first 2 weeks, then 3x/week
Body Zonevariable
Evidence LevelEmerging

Mechanism of Action

NIR light stimulates osteoblast proliferation and differentiation, enhances BMP-2 expression, increases local blood flow to the fracture site, and accelerates the transition from soft callus to hard callus. It also reduces fracture-related inflammation and pain.

Key Studies

  • Pretel et al. (2007) - PBM effects on bone healing in rats
  • Medalha et al. (2012) - PBM for bone repair

Treatment Tips

  • *Apply through cast if present (NIR penetrates most cast materials)
  • *Coordinate with orthopedic surgeon
  • *Do not replace standard fracture management
  • *Adequate calcium, vitamin D, and protein support healing

Contraindications

  • !Open fractures with active infection
  • !Bone malignancy

Research Basis

This content is informed by 47+ published peer-reviewed studies on photobiomodulation.